Protein Purification
MilliporeSigma™ Calbiochem™ ETV1 Inhibitor, BRD32048
Cell-permeable, reversibly binds to ETV1 (KD = 17.1 μM) and reduces its transcriptional activity, independent of its binding to DNA.
MilliporeSigma™ Calbiochem™ Dkk Inhibitor II, IIIC3a
An enhanced in solution stable gallocyanine analog that directly and reversibly targets human LRP5/6 (low density lipoprotein-related protein 5/6), and disrupts its interaction with Dkk (Dickkopf) in a competitive manner
MilliporeSigma™ Calbiochem™ H-89, Dihydrochloride
A cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase A (Ki = 48 nM).
MilliporeSigma™ Calbiochem™ Collagenase Inhibitor I
The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor XII, TWS119
The GSK-3β Inhibitor XII, TWS119, also referenced under CAS 601514-19-6, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 1-Pyrrolidinecarbodithioic Acid, Ammonium Salt
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
MilliporeSigma™ Calbiochem™ HSP90 Inhibitor, CCT018159
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
MilliporeSigma™ Calbiochem™ GPR40 Agonist III
A cell-permeable, highly potent, and selective agonist of free fatty acid receptor 1 (FFA1; GPR40; EC50 = 20 nM in FFA1-transfected HEK-293 cells).
MilliporeSigma™ Calbiochem™ ICMT Inhibitor
The ICMT Inhibitor controls the biological activity of ICMT. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ PTP1B Inhibitor
The InSolution™ PTP1B Inhibitor controls the biological activity of PTP1B. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ CCR2 Antagonist
The CCR2 Antagonist, also referenced under CAS 445479-97-0, controls the biological activity of CCR2.
MilliporeSigma™ Calbiochem™ GPR40 Agonist
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
MilliporeSigma™ Calbiochem™ Pirenzepine Dihydrochloride
An antagonist selective for mAChR subtype M1.